منابع مشابه
Hemodynamics of angiotensin in man.
RECENTLY, synthetic angiotensin II has become available for study. Page and Helmer1 and Braun-Menendez and cowork-ers2 have demonstrated that this compound represents the reaction product of renin on the a2 globulin, hypertensinogen. Intensive pharmacologic studies conducted by the Cleveland group3-5 and the Swiss6, 7 have verified that synthetic angiotensin II is identical with the naturally o...
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15 صفحه اولHemodynamics of a new angiotensin antagonist, [Sar1, Thr8]A II, in hypertensive man.
SUMMARY Hemodynamic responses to a new angiotensin II antagonist, [Sarl, Thr8]A II, were studied in 17 hypertensive patients whose plasma renin activity (PRA) ranged from 0.2-42.0 ng/ml/hr. With infusion of 1.0 gg/kg/min, mean arterial pressure (MAP) rose 10 mm Hg in six patients, was unchanged in six patients, and decreased 2 10 mm Hg in five patients. There was no significant change in either...
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Serial measurements of glomerular filtration rate (GFR), independent and simultaneous clearances and extractions of para-aminohippurate (PAH), radiohippuran, and iodopyracet (Diodrast) were made in 11 adults and one child who received renal transplants from living donors. Measurements were made within 3 hours and repeated two to four times during the following 14 days. Immediately after transpl...
متن کاملAngiotensin dependence of endothelium-mediated renal hemodynamics.
Endothelium-derived relaxing factor has been shown to regulate renal blood flow, and inhibition of its synthesis increases blood pressure and renal vascular resistance and decreases renal blood flow. Using the substrate antagonist NW-nitro-L-arginine methyl ester (L-NAME), we tested whether renal vasoconstriction induced by endothelium-derived relaxing factor synthesis inhibition could be media...
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ژورنال
عنوان ژورنال: Circulation
سال: 1962
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.25.1.255